[Dysphagia] Ehlers Danlos Syndrome and radiation

[bonnieh4455 at sbcglobal.net (Bonnie Heintskill)]

Titre du document / Document title
Induction and subsequent rupture of aneurysms of the circle of Willis after radiation therapy in Ehlers-Danlos syndrome : a plausible hypothesis 
Auteur(s) / Author(s)
HOLODNY A. I. (1) ; DECK M. ; PETITO C. K. (1) ; 
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) New York hosp-Cornell univ. medical coll., dep. pathology (neuropathology), New York NY 10016, ETATS-UNIS

R?sum? / Abstract
Multiple aneurysms of the circle of Willis developed in a 62-year-old woman with Ehlers-Danlos syndrome (EDS) within 7 months of initiation of radiation therapy to the brain. A major response of the arterial wall to radiation damage is the formation of collagen. In patients with EDS, in whom there is a defect in collagen, this repair is incomplete. We propose that the incomplete repair of the arterial wall consequent to EDS resulted in weakness of these walls, formation of an aneurysm, and, ultimately, fatal subarachnoid hemorrhage. 
Revue / Journal Title
American journal of neuroradiology  (Am. j. neuroradiol.)  ISSN 0195-6108   CODEN AAJNDL  
Source / Source
1996, vol. 17, no2, pp. 226-232 (38 ref.) 
Langue / Language
Anglais

Editeur / Publisher
American Society of Neuroradiology, Oak Brook, IL, ETATS-UNIS (1980) (Revue)

Mots-cl?s anglais / English Keywords
Ehlers Danlos syndrome ; Aneurysm ; Circulus arteriosus of Willis ; Radiotherapy ; Malignant tumor ; Mammary gland ; Nuclear magnetic resonance imaging ; Case study ; Complication ; Iatrogenic ; Human ; Female ; Metastasis ; Intracranial ; Skin disease ; Elastic tissue disease ; Diseases of the osteoarticular system ; Systemic disease ; Genetic disease ; Nervous system diseases ; Central nervous system disease ; Cerebral disorder ; Cerebrovascular disease ; Cardiovascular disease ; Vascular disease ; Arterial disease ; Mammary gland diseases ; 
Mots-cl?s fran?ais / French Keywords
Ehlers Danlos syndrome ; An?vrysme ; Polygone art?riel Willis ; Radioth?rapie ; Tumeur maligne ; Glande mammaire ; Imagerie RMN ; Etude cas ; Complication ; Iatrog?ne ; Homme ; Femelle ; M?tastase ; Intracr?nien ; Peau pathologie ; Tissu ?lastique pathologie ; Syst?me ost?oarticulaire pathologie ; Maladie syst?me ; Maladie h?r?ditaire ; Syst?me nerveux pathologie ; Syst?me nerveux central pathologie ; Enc?phale pathologie ; C?r?brovasculaire pathologie ; Appareil circulatoire pathologie ; Vaisseau sanguin pathologie ; Art?re pathologie ; Glande mammaire pathologie ; 

002b26i ; 
Mots-cl?s espagnols / Spanish Keywords
Piel el?stica ; Aneurisma ; Pol?gono arterial Willis ; Radioterapia ; Tumor maligno ; Gl?ndula mamaria ; Imageria RMN ; Estudio caso ; Complicaci?n ; Iatr?geno ; Hombre ; Hembra ; Met?stasis ; Intracraneal ; Piel patolog?a ; Tejido el?stico patolog?a ; Sistema osteoarticular patolog?a ; Enfermedad sist?mica ; Enfermedad hereditaria ; Sistema nervioso patolog?a ; Sistema nervosio central patolog?a ; Enc?falo patolog?a ; Vaso sangu?neo enc?falo patolog?a ; Aparato circulatorio patolog?a ; Vaso sangu?neo patolog?a ; Arteria patolog?a ; Gl?ndula mamaria patolog?a ; 
Localisation / Location
INIST-CNRS, Cote INIST : 19668, 35400005295861.0040


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